Dr. SUNITA CHAURASIA

Abstract

Purpose: To report the clinical profile and donor characteristics of post keratoplasty adverse events notified at an eye bank. Results : During the study period, of the 26,271 donor corneas, 39 recipients had post keratoplasty infections. Majority (77%) were noted after EK (27 after DSAEK, and 3 after DMEK), 2 after DALK, 7 after PK; GNB 18, fungus 3, gram positive i2, mixed organisms 4 and microbiology inconclusive 12. All gram-negative species were multi-drug resistant. Donor mortality causes: polytrauma 23, cardiorespiratory arrest 13, organophosphorus poisoning 2 , natural causes 1.The mean duration of presentation was 6.84 (Range 1-80) days. The death to preservation time was 5.16 (1-21) hours. 13 corneas were retrieved from mortuary. The death to utilization time was 3.4(1- 8) days. Discussion: Majority (82%) of the adverse events were following lamellar surgeries, of which DSEK was the commonest. Gram-negative bacteria dominated majority of the bacterial infections.