DR. RAJWINDER KAUR BHATTAL

Abstract

PURPOSE: To determine the effect of Transcutaneous Retrobulbar amphotericin B (TRAMB) injection on orbital manifestations in two cases of COVID- 19 related ROCM in a tertiary care centre.

METHODS: The retrospective analytical study was conducted over the time period of four months. Histologically and radiologically confirmed two in-patients of Mucormycosis were considered for TRAMB after detailed ocular examination. Follow-up of patients was done daily and repeated TRAMB injections were considered accordingly.RESULT: The age of patients ranged from 35-50 years and with history of COVID infection. Co – morbidities noted were diabetes (n-1), and HTN (n-0). Both patients showing focal involvement of one or more extraocular muscles were given 0.3mg/ml transcutaneous retrobulbar amphotericin B. Patients showed significant improvement with successive doses of TRAMB.CONCLUSION: In the setting of progressive orbital disease, retrobulbar amphotericin B treatment should be considered.